Bench-to-bedside

During the event, several case studies were presented to illustrate successful transitions from research to clinical practice. Notably, Blink Lab was highlighted as an exemplary case. This start-up has developed a mobile phone application that enables remote neurobehavioral evaluations, aiding research on conditions like schizophrenia, autism, ADHD, and various forms of dementia. The technology’s ability to conduct large-scale, at-home testing through smartphone-based eyeblink conditioning and prepulse inhibition tests demonstrated innovative methods for early detection and monitoring of neurological disorders.

Participants also explored the Tailored Program, a collaboration aimed at developing personalized genetic therapies for neurodevelopmental disorders. This initiative, led by Prof. De Vrij, emphasized the use of human neuronal iPSCs for therapeutic discovery and highlighted the challenges and strategies in pushing such niche therapies towards commercialization.

Another significant discussion centered around the ENCORE program, which integrates multidisciplinary expertise to deliver specialized care and develop new treatments for rare genetic neurocognitive diseases. The program’s emphasis on combining basic and clinical research to improve patient outcomes provided valuable insights into the importance of a collaborative, patient-centered approach in medical research.