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Reportage: 165 million Europeans suffer from various types of mental disorders and brain diseases every year. These are data from a report by the European College of Neuropsychopharmacology. Such diseases include depression, anxiety disorders, Parkinson’s disease, and dementia. The Polish Centre for Technology Development Łukasiewicz—PORT will soon implement the SAME-NeuroID project, which received a Twinning grant from the Horizon Europe programme, within which scientists will study, among other things, the neurobiological basis of psychiatric diseases. In the future, this may result in the development of new pharmacological methods for treating such diseases.
Notice: reportage is in polish.
From an evolutionary perspective, the answer to the question – to eat or not to eat? – is quite simple and obvious. The matter becomes more complicated with the civilizational development of modern societies. Why is this so? It turns out that the solution to this riddle is in the brain.
We invite you to watch the lecture by Dr. Hab. Witold Konopka, entitled: “To eat or not to eat, or the brain versus the body”.
Notice: lectureis in polish.
The 2023 edition of #PORTforHealth conference focuses on biological models and computational approaches to understand brain disorders. Participants will have the opportunity to listen to over 20 lectures presenting the latest research findings and achievements in the field of neuropsychiatry, neurodegeneration, and neuro-metabolic disorders.
The organizer behind #PORTforHealth is Łukasiewicz Research Network – PORT Polish Center for Technology Development, located in #Wrocław. The Life Sciences and Biotechnology Center at Łukasiewicz – PORT is committed to addressing the most pressing challenges of modern medicine through cutting-edge translational research conducted by teams led by visionary and experienced leaders.
Lecture: The Interplay between Metabolism and Epigenetics in Risk and Transmission of Neuropsychiatric Disorders
Can Parental Exposures lead to Heritable Effects? What is a role for Metabolism in Neurodegeneration? These and other questions had been raised and answered on Ali Jawaid’s, Ph.D. lecture, given at Łukasiewicz – PORT Polish Center for Technology Development on 30th March 2023.
Ali Jawaid, Ph.D. is a physician-scientist with training in both clinical and basic neuroscience. He heads the Laboratory for Translational Research in Neuropsychiatric Disorders (TREND lab) at the BRAINCITY, Warsaw, Poland. TREND
Prof. Leszek Kaczmarek, Professor at the Nencki Institute of Experimental Biology, Polish Academy of Sciences, Warsaw, Poland, and head of the Laboratory of Neurobiology. Seminar Title: “From c-Fos to MMP-9 as a drug target in development of epilepsy”
SAME-NeuroID scientific seminar featuring Professor Bastian Hengerer, the Director of CNS Diseases Research at Boehringer Ingelheim. Professor Hengerer will present the key findings of his research.
Seminar Title: “Studying the Circuit Biology of Social Behavior: Backtranslation of the Findings of a Transdiagnostic Clinical Study“
PRISM (Psychiatric Ratings using Intermediate Stratified Markers), an EU-wide consortium, has uncovered a transdiagnostic link between neural integrity in the brain’s Default Mode Network (DMN) and social dysfunction. Professor Hengerer presented groundbreaking findings, providing a neurobiological framework for further validation.
Research in Prof. Rust’s lab focuses on deciphering the molecular mechanisms controlling neuronal actin dynamics and understanding the relevance of actin regulators in the development and function of the mammalian brain. Prof. Rust’s team has identified actin-depolymerizing proteins of the ADF/cofilin family as pivotal regulators in neurons, impacting the morphology and function of excitatory synapses. Their exploration extends to understanding the role of cyclase-associated protein (CAP), which recent studies suggest may collaborate with ADF/cofilin in neuronal functions. By investigating CAP1 and CAP2 in the brain, particularly in dendritic spines, the team has revealed their involvement in regulating actin dynamics and their interdependence with cofilin1, along with their roles in controlling dendritic spine maturation.
Webinar Highlights:
• Introduction to the SAME-NeuroID project and presentation on the research activities within the project by Agnieszka Krzyżosiak, PhD and Michał Ślęzak, PhD.
• Presentation of the NeuroHack event and the overview of the selection process for group leaders through One-Pagers by Bertrand Dupont, PhD.
With a relentless pursuit of knowledge, we unravel the complexities of the mind, unraveling the mysteries that hinder mental well-being. Join us as we pave the way for breakthroughs in neuroscience and offer hope for a brighter future
With unwavering determination, we delve into the depths of the human mind, pioneering breakthroughs that inspire a brighter future for mental well-being and transform lives.
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