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SCIENTIFIC SEMINARS
SAME-NeuroID scientific seminar featuring Professor Bastian Hengerer, Director of CNS Diseases Research at Boehringer Ingelheim, took a place on February 1st 2024.
Seminar Title: “Studying the Circuit Biology of Social Behavior: Backtranslation of the Findings of a Transdiagnostic Clinical Study”
Abstract: “PRISM (Psychiatric Ratings using Intermediate Stratified Markers), a EU wide consortium of academic and industry partners, identified a novel transdiagnostic and pathophysiological link between quantitative measures of neural integrity within the brain’s Default Mode Network (DMN) and social dysfunctioning. Significant relationships of measures of daily social functioning with quantitative neuroimaging measures of DMN activity and DMN connectivity were observed irrespective of the initial clinical diagnosis. These findings are providing a novel neurobiological, quantitative, and transdiagnostic framework for further validation.
To enrich our understanding of the fundamental biology underlying the new hypotheses and to test the causality between the quantitative variation in DMN integrity and social dysfunction in preclinical models, the team modulated DMN activity experimentally and developed a novel setup for automated analysis of social behavior in groups of mice.”
Short Bio:
Professor Bastian Hengerer has more than 34 years’ experience in pharmaceutical industry. Currently the Director of CNS Diseases Research at Boehringer Ingelheim, he joined Boehringer Ingelheim in 2003, heading the preclinical Parkinson’s disease research group and now being responsible for scientific partnering in the field of CNS Diseases.
As usual, for young investigators, there was a post-lecture meeting scheduled as a Q&A session. During this session, they had the opportunity to ask our guest questions, such as how to accelerate their careers.
This seminar is part of the SAME-NeuroID project funded by the Horizon Europe program.
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